Investigating the Mechanisms of AquaporinZ Reconstitution through Polymeric Vesicle Composition for a Biomimetic Membrane
作者： Danhua Zhou , Hu Zhou , Shufeng Zhou , Yen Wah Tong
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摘要: Aquaporin-Z (AqpZ) are water channel proteins with excellent permeability and solute rejection properties. AqpZ can be reconstituted into vesicles utilizing cell-like bilayer membranes assembled from amphiphilic block copolymers, for the preparation of high-performance biomimetic membranes. However, only a few copolymers have been found suitable to act as membrane matrix protein reconstitution. Hence, this work analyzes mechanism reconstitution based on composition-reconstitution relationship. The vesicle formation processes in various were investigated terms size, morphology, stability, polymeric rigidity, thermal behavior. Overall, study contributes understanding relationship AqpZ-reconstituted vesicles.
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Tiziana Parasassi, Ewa K. Krasnowska, Luis Bagatolli, Enrico Gratton, Laurdan and Prodan as Polarity-Sensitive Fluorescent Membrane Probes Journal of Fluorescence. ,vol. 8, pp. 365- 373 ,(1998) , 10.1023/A:1020528716621
Liao Y. Chen, Erythritol predicted to inhibit permeation of water and solutes through the conducting pore of P. falciparum aquaporin Biophysical Chemistry. ,vol. 198, pp. 14- 21 ,(2015) , 10.1016/J.BPC.2015.01.004
Wenyuan Xie, Fang He, Bingfang Wang, Tai-Shung Chung, Kandiah Jeyaseelan, Arunmozhiarasi Armugam, Yen Wah Tong, None, An aquaporin-based vesicle-embedded polymeric membrane for low energy water filtration Journal of Materials Chemistry. ,vol. 1, pp. 7592- 7600 ,(2013) , 10.1039/C3TA10731K
Mario J Borgnia, David Kozono, Giuseppe Calamita, Peter C Maloney, Peter Agre, Functional reconstitution and characterization of AqpZ, the E. coli water channel protein. Journal of Molecular Biology. ,vol. 291, pp. 1169- 1179 ,(1999) , 10.1006/JMBI.1999.3032
Yubo Zhang, Yubao Cui, L.Y. Chen, Mercury inhibits the L170C mutant of aquaporin Z by making waters clog the water channel. Biophysical Chemistry. ,vol. 160, pp. 69- 74 ,(2012) , 10.1016/J.BPC.2011.07.006
Hyo-Jick Choi, Carlo Montemagno, Recent Progress in Advanced Nanobiological Materials for Energy and Environmental Applications Materials. ,vol. 6, pp. 5821- 5856 ,(2013) , 10.3390/MA6125821
Wenming Shen, Jinhua Hu, Xiao Hu, Impact of amphiphilic triblock copolymers on stability and permeability of phospholipid/polymer hybrid vesicles Chemical Physics Letters. ,vol. 600, pp. 56- 61 ,(2014) , 10.1016/J.CPLETT.2014.03.057
Yue-xiao Shen, Patrick O. Saboe, Ian T. Sines, Mustafa Erbakan, Manish Kumar, Biomimetic membranes: A review Journal of Membrane Science. ,vol. 454, pp. 359- 381 ,(2014) , 10.1016/J.MEMSCI.2013.12.019
Bohdana M Discher, You-Yeon Won, David S Ege, James CM Lee, Frank S Bates, Dennis E Discher, Daniel A Hammer, Polymersomes: Tough Vesicles Made from Diblock Copolymers Science. ,vol. 284, pp. 1143- 1146 ,(1999) , 10.1126/SCIENCE.284.5417.1143
MaryTheresa M. Pendergast, Eric M.V. Hoek, A review of water treatment membrane nanotechnologies Energy and Environmental Science. ,vol. 4, pp. 1946- 1971 ,(2011) , 10.1039/C0EE00541J