Solving the Issue of Restenosis After Stenting of Intracranial Stenoses: Experience with Two Thin-Strut Drug-Eluting Stents (DES)—Taxus Element™ and Resolute Integrity™

作者: Wiebke Kurre , Marta Aguilar-Pérez , Sebastian Fischer , Guy Arnold , Elisabeth Schmid

DOI: 10.1007/S00270-014-1001-3

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摘要: Thin-strut, flexible DES are suitable for intracranial stenting and may improve long-term vessel patency. The purpose of this study was to report our experience with two new-generation the treatment atherosclerotic disease. We retrospectively reviewed all patients treated Taxus Element™ or Resolute Integrity™ stent an stenosis between March 2011 August 2013. Technical success defined as ability deploy device at desired location reduce degree below 50 %. All procedure-related strokes were recorded. Control angiography scheduled after 6 weeks, 3, 6, 12 months yearly thereafter. A luminal narrowing ≥50 % regarded a restenosis. Stroke recurrence in territory artery reported. In period we 101 harboring 117 stenoses. procedure successful 100 (85.5 %) lesions. Procedure-related occurred 10 (9.9 %) permanent morbidity 3 (3.0 %). Follow-up available 83 (83.0 %) successfully lesions average 355 days (IQR 153–482 days). Three (3.6 %) asymptomatic restenoses detected. Integrity™, none (p = 0.059). New encountered 2 (2.6 %) occasions. Thin-strut patency risk subsequent stroke. Differences devices exist. Feasibility is comparable bare-metal balloon-mounted stents within expected range.

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