Mechanism by Which Mcl-1 Regulates Cancer-Specific Apoptosis Triggered by mda-7/IL-24, an IL-10–Related Cytokine

作者: Rupesh Dash , Joanna E. Richards , Zhao-zhong Su , Sujit K. Bhutia , Belal Azab

DOI: 10.1158/0008-5472.CAN-10-0563

关键词:

摘要: … Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24), a cytokine belonging to the IL-10 family, selectively induces apoptosis in cancer cells without harming normal …

参考文章(39)
Ping Zhou, Liping Qian, Karen M. Kozopas, Ruth W. Craig, Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood. ,vol. 89, pp. 630- 643 ,(1997) , 10.1182/BLOOD.V89.2.630
Shinichi Kitada, Maryla Krajewska, Jurgita Sauvageot, Ahmed Shabaik, Stanislaw Krajewski, Jonathan I. Epstein, John C. Reed, Ki Song, Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. American Journal of Pathology. ,vol. 148, pp. 1567- 1576 ,(1996)
Dale A Moulding, Richard V Giles, David G Spiller, Michael RH White, David M Tidd, Steven W Edwards, None, Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells. Blood. ,vol. 96, pp. 1756- 1763 ,(2000) , 10.1182/BLOOD.V96.5.1756.H8001756_1756_1763
Shinichi Kitada, Irina V Lebedeva, Samuel Waxman, Zao-Zhong Su, Paul Dent, Devanand Sarkar, Paul B Fisher, John C Reed, Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species. Cancer Research. ,vol. 63, pp. 8138- 8144 ,(2003)
Luni Emdad, Irina V. Lebedeva, Zhao-zhong Su, Pankaj Gupta, Moira Sauane, Rupesh Dash, Steven Grant, Paul Dent, David T. Curiel, Devanand Sarkar, Paul B. Fisher, Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biology & Therapy. ,vol. 8, pp. 391- 400 ,(2009) , 10.4161/CBT.8.5.7581
R Dash, I Dmitriev, Z-z Su, S K Bhutia, B Azab, N Vozhilla, A Yacoub, P Dent, D T Curiel, D Sarkar, P B Fisher, Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells. Cancer Gene Therapy. ,vol. 17, pp. 447- 456 ,(2010) , 10.1038/CGT.2009.91
B. FADEEL, S. ORRENIUS, Apoptosis : a basic biological phenomenon with wide-ranging implications in human disease Journal of Internal Medicine. ,vol. 258, pp. 479- 517 ,(2005) , 10.1111/J.1365-2796.2005.01570.X
M. Sauane, Z.-z. Su, P. Gupta, I. V. Lebedeva, P. Dent, D. Sarkar, P. B. Fisher, Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 9763- 9768 ,(2008) , 10.1073/PNAS.0804089105
Ralph M. Fritsch, Günter Schneider, Dieter Saur, Melanie Scheibel, Roland M. Schmid, Translational Repression of MCL-1 Couples Stress-induced eIF2α Phosphorylation to Mitochondrial Apoptosis Initiation Journal of Biological Chemistry. ,vol. 282, pp. 22551- 22562 ,(2007) , 10.1074/JBC.M702673200
Paul Fisher, John Nemunaitis, Neil Senzer, Paul Dent, Steven Grant, Adly Yacoub, David Curiel, Igor Dmitriev, Parameshwar Mahasreshti, Anthony De Pass, Satoshi Inoue, Sunil Chada, Rong Li, Rajagopal Ramesh, Habib Boukerche, Lejuan Chatman, Eun Park, Dongning Wang, Nicollaq Vozhilla, Seok-Geun Lee, Paola Barral, Ruoyu Xiao, Mohiuddin Taher, Shi-Jian Liu, Moira Sauane, Devanand Sarkar, Michelle Staudt, Pankaj Gupta, Zao-Zhong Su, Luni Emdad, Irina Lebedeva, mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). International Journal of Oncology. ,vol. 31, pp. 985- 1007 ,(2007) , 10.3892/IJO.31.5.985