Influence of erosion of calcium-induced alginate gel matrix on the release of Brilliant Blue

作者: Y. Murata , K. Nakada , E. Miyamoto , S. Kawashima , Seung-Hoon Seo

DOI: 10.1016/0168-3659(93)90067-F

关键词:

摘要: Abstract The relationship between the release of a dye (Brilliant Blue; BB) incorporated in calcium-induced alginate gels and erosion gel itself was investigated. rate BB from formed low-molecular-weight faster than that high-molecular-weight alginate, also former case. As concentration increased, both controlled. No remarkable differences were found among two kinds alginates with different monomeric composition. Furthermore, some decayed aqueous media containing sufficient levels univalent cations. It confirmed accelerates them.

参考文章(10)
L.S. Shenouda, K.A. Adams, M.A. Zoglio, A controlled release delivery system using two hydrophilic polymers International Journal of Pharmaceutics. ,vol. 61, pp. 127- 134 ,(1990) , 10.1016/0378-5173(90)90051-5
Yoshifumi Murata, Susumu Kawashima, Etsuko Miyamoto, Noriko Masauji, Akiko Honda, Colorimetric determination of alginates and fragments thereof as the 2-nitrophenylhydrazides Carbohydrate Research. ,vol. 208, pp. 289- 292 ,(1990) , 10.1016/0008-6215(90)80114-I
Mary M. Welz, Clyde M. Ofner, Examination of Self-Crosslinked Gelatin as a Hydrogel for Controlled Release Journal of Pharmaceutical Sciences. ,vol. 81, pp. 85- 90 ,(1992) , 10.1002/JPS.2600810117
Chong-Kook Kim, Eun-Jin Lee, The controlled release of blue dextran from alginate beads International Journal of Pharmaceutics. ,vol. 79, pp. 11- 19 ,(1992) , 10.1016/0378-5173(92)90088-J
Olav Smidsrød, Arne Haug, Stuart G. Whittington, Elisabeth Sjöstrand, Sigfrid Svensson, The Molecular Basis for Some Physical Properties of Polyuronides. Acta Chemica Scandinavica. ,vol. 26, pp. 2563- 2566 ,(1972) , 10.3891/ACTA.CHEM.SCAND.26-2563
Attilio Cesàro, Franco Delben, Sergio Paoletti, Interaction of divalent cations with polyuronates Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases. ,vol. 84, pp. 2573- 2584 ,(1988) , 10.1039/F19888402573
Toshihisa YOTSUYANAGI, Isamu YOSHIOKA, Naoki SEGI, Ken IKEDA, Acid-induced and calcium-induced gelation of alginic acid: Bead formation and pH-dependent swelling. Chemical & Pharmaceutical Bulletin. ,vol. 39, pp. 1072- 1074 ,(1991) , 10.1248/CPB.39.1072
Susumu KAWASHIMA, Norio NISHIURA, Tatsumi NOGUCHI, Hiroshi FUJIWARA, Studies on sustained-release suppositories. I. Effect of alginic acid addition on rectal absorption of bacampicillin in rabbits. Chemical & Pharmaceutical Bulletin. ,vol. 37, pp. 766- 770 ,(1989) , 10.1248/CPB.37.766