Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.

作者: B.T. Pentecost , C.T. Teng

DOI: 10.1016/S0021-9258(18)61088-9

关键词:

摘要: Antibody to an estrogen inducible mouse uterine protein (Teng, C. T., Walker, M. P., Bhattacharyya, S. N., Klapper, D. G., DiAugustine, R. and McLachlan, J. A. (1986) Biochem. 240, 413-422) has been used isolate cDNA the messenger RNA. Analysis of deduced primary structure additional biochemical characterization indicates that is lactotransferrin. An increase in level lactotransferrin mRNA at least 300-fold can be induced uterus by estrogen. In contrast, virtually undetectable rat tissue following administration. The estrogenic stimulation contrasts with known prolactin dependence mammary gland.

参考文章(49)
D B Lubahn, K S McCarty, K S McCarty, Electrophoretic characterization of purified bovine, porcine, murine, rat, and human uterine estrogen receptors. Journal of Biological Chemistry. ,vol. 260, pp. 2515- 2526 ,(1985) , 10.1016/S0021-9258(18)89583-7
D.R. Tourville, S.S. Ogra, J. Lippes, T.B. Tomasi, The human female reproductive tract: Immunohistological localization of γA, γG, γM, secretory “piece,” and lactoferrin American Journal of Obstetrics and Gynecology. ,vol. 108, pp. 1102- 1108 ,(1970) , 10.1016/0002-9378(70)90460-6
R D Klausner, J Van Renswoude, G Ashwell, C Kempf, A N Schechter, A Dean, K R Bridges, Receptor-mediated endocytosis of transferrin in K562 cells Journal of Biological Chemistry. ,vol. 258, pp. 4715- 4724 ,(1983) , 10.1016/S0021-9258(18)32481-5
R T MacGillivray, E Mendez, J G Shewale, S K Sinha, J Lineback-Zins, K Brew, The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure. Journal of Biological Chemistry. ,vol. 258, pp. 3543- 3553 ,(1983) , 10.1016/S0021-9258(18)32696-6
Rafael Palacios, Richard D. Palmiter, Robert T. Schimke, Identification and Isolation of Ovalbumin-synthesizing Polysomes I. SPECIFIC BINDING OF 125I-ANTI-OVALBUMIN TO POLYSOMES Journal of Biological Chemistry. ,vol. 247, pp. 2316- 2321 ,(1972) , 10.1016/S0021-9258(19)45431-8
Richard D. Palmiter, Regulation of Protein Synthesis in Chick Oviduct Journal of Biological Chemistry. ,vol. 247, pp. 6450- 6459 ,(1972) , 10.1016/S0021-9258(19)44713-3
M K Skinner, W L Cosand, M D Griswold, Purification and characterization of testicular transferrin secreted by rat Sertoli cells. Biochemical Journal. ,vol. 218, pp. 313- 320 ,(1984) , 10.1042/BJ2180313
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
C T Teng, M P Walker, S N Bhattacharyya, D G Klapper, R P DiAugustine, J A McLachlan, Purification and properties of an oestrogen-stimulated mouse uterine glycoprotein (approx. 70 kDa) Biochemical Journal. ,vol. 240, pp. 413- 422 ,(1986) , 10.1042/BJ2400413