Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate.
作者： Mysore Bhyrappa Harisha , Pandi Dhanalakshmi , Rajendran Suresh , Raju Ranjith Kumar , Shanmugam Muthusubramanian
DOI: 10.3762/BJOC.16.178
关键词:
摘要: The reactivity of α-azidochalcones has been explored for the preparation highly substituted oxazoles via a 2H-azirine intermediate. azidochalcones, when treated with potassium thiocyanate in presence persulfate, lead to 2,4,5-trisubstituted good yields. Incidentally, 2-aminothiazoles are products ferric nitrate is employed instead persulfate above reaction.
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