Compliance with a critical pathway for the management of febrile neutropenia and impact on clinical outcomes.

摘要: Febrile neutropenia is associated with significant morbidity and mortality. Managing infectious in neutropenic patients remains a dynamic process, making necessary timely efficient empirical antibiotic therapy. The implementation of critical pathways has been suggested as strategy to improve clinical effectiveness. This study evaluated the compliance an institutional pathway for management febrile impact on outcomes at Hospital de Clinicas Porto Alegre, Brazil (HCPA). We performed cohort that prospectively included hospitalized from January 2004 December 2005 presented (190 episodes). Historical controls were selected March 2001 April 2003 (193 episodes) before was introduced. showed low rate full (21.6%; 95% CI 15.7–27.5) pathway. In most cases, there partial (67.9%; 61.3–74.5). Despite moderate adherence observed, we recorded decrease in-hospital all-cause mortality sample studied after protocol (from 24.4 14.4%; P = 0.017) reduction length use cephalosporin quinolones. conclusion, seems be effective neutropenia.