Atmospheric Pressure Chemical Ionization Interface for Capillary Electrophoresis/Mass Spectrometry

摘要: Capillary electrophoresis/atmospheric pressure chemical ionization mass spectrometry (CE/APCI-MS) is described. The interface between capillary electrophoresis and consists of an electrospray-tye nebulizer, a vaporizer, atmospheric source using needle electrode. In this system, solution nebulized by electrospray, vaporized samples are ionized corona discharge followed ion/molecule reactions. Protonated caffeine molecules obtained CE/APCI-MS with sodium phosphate buffers. very promising technique because the APCI process not heavily affected salts in CE buffers, allowing use variety buffers CE/MS analysis