Nucleic acid molecules encoding a 103 gene product and uses therefor
作者： Gillian A. Kingsbury , Kevin R. Leiby
DOI:
关键词:
摘要: The present invention relates to methods and compositions for the treatment diagnosis of immune disorders, especially T helper lymphocyte-related disorders. In particular, provides a nucleotide sequence which encodes previously unknown human 103 gene product. also expression vectors containing nucleic acid molecules host cells into have been introduced. still further isolated polypeptides, fusion antigenic peptides antibodies.
lens.org 参考文章(73)
G. Bergers, A. Reikerstorfer, S. Braselmann, P. Graninger, M. Busslinger, Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. The EMBO Journal. ,vol. 13, pp. 1176- 1188 ,(1994) , 10.1002/J.1460-2075.1994.TB06367.X
Leo T. Furcht, Kevin L. Billups, Sharon M. Wahl, Jeffrey E. Everett, Janice B. Allen, James B. McCarthy, Method for treating ischemia using polypeptides with fibronectin activity Official Gazette of the United States Patent and Trademark Office Patents. ,vol. 121, pp. 4006- ,(1995)
P. Y. Lin, L. H. Y. Young, Shue-Fen Luo, Chau-Ching Liu, Li Mou Zheng, J. D.-E. Young, S. V. Joag, Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis. American Journal of Pathology. ,vol. 140, pp. 1261- 1268 ,(1992)
L.M. Wang, A.D. Keegan, W.E. Paul, M.A. Heidaran, J.S. Gutkind, J.H. Pierce, IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells. The EMBO Journal. ,vol. 11, pp. 4899- 4908 ,(1992) , 10.1002/J.1460-2075.1992.TB05596.X
F. Y. Liew, Induction and Regulation of CD4+ T Cell Subsets Ciba Foundation Symposium 187 - Vaccines Against Virally Induced Cancers. ,vol. 187, pp. 170- 178 ,(1994) , 10.1002/9780470514672.CH11
B E Torbett, G S Firestein, C T Weaver, J T Hom, K S Townsend, W D Roeder, J A Laxer, J Linton, A L Glasebrook, A new murine CD4+ T cell subset with an unrestricted cytokine profile. Journal of Immunology. ,vol. 143, pp. 518- 525 ,(1989)
Heidrun Moll, Christoph Müller, Reinhard Gillitzer, Harald Fuchs, Martin Röllinghoff, Markus M Simon, Michael D Kramer, Expression of T-cell-associated serine proteinase 1 during murine Leishmania major infection correlates with susceptibility to disease. Infection and Immunity. ,vol. 59, pp. 4701- 4705 ,(1991) , 10.1128/IAI.59.12.4701-4705.1991
Samantha J. Busfield, Novel molecules of the tnf receptor superfamily and uses therefor ,(1998)
Method for treating acute and chronic inflammatory disorders using polypeptides with fibronectin activity Biotechnology Advances. ,vol. 15, ,(1992) , 10.1016/S0734-9750(97)88706-X
C.J. McMahan, J.L. Slack, B. Mosley, D. Cosman, S.D. Lupton, L.L. Brunton, C.E. Grubin, J.M. Wignall, N.A. Jenkins, C.I. Brannan, A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. The EMBO Journal. ,vol. 10, pp. 2821- 2832 ,(1991) , 10.1002/J.1460-2075.1991.TB07831.X