Naphtholactams and lactones as bone morphogenetic protein active agents

作者: Kohei Notoya , Masaki Ogino , Masatoshi Hazama , Shogo Marui

DOI:

关键词:

摘要: A compound of formula (I) wherein Q is an optionally substituted carbon atom or N(O)p p 0 1; Y methylene group, S(O)q q integer to 2, imino group; Z1 a C?1-3? alkylene group which may have oxo thioxo and contain etherified oxygen sulfur within the chain; Z?2? Ar carbocyclic heterocyclic one R?1 R2? hydrogen atom, halogen hydroxyl lower alkyl alkoxy other taken together with adjacent -c=c- form ring; ring benzene be in addition R2?; salt thereof.

参考文章(17)
Shozo Takechi, Teruhisa Ichihashi, Sachio Mori, Takuji Mizui, Shiro Kida, Lignan analog, production thereof, and hypolipidemic drug. ,(1992)
Hiroshi Ohmizu, Tameo Iwasaki, Masami Takahashi, Process for preparing a naphthalene derivative and a synthetic intermediate thereof ,(1990)
James L Diebold, Milton Wolf, 3 4-dihydroacridin-2-(1h)-one derivatives ,(1970)
Hideaki Natsugari, Hitoshi Ikeda, Takayuki Doi, Takenori Ishimaru, Condensed heterocyclic compounds, their production and use ,(1993)
James L Diebold, Milton Wolf, 2-(benzonaphthyridin-2-yl acyl) benzonaphthyridines ,(1968)
James L Diebold, Milton Wolf, 5-arylbenzo (b) (1,7) naphthyridine derivatives ,(1970)
Gerhart Dipl Chem Dr Griss, Wolfgang Dipl Chem Dr Grell, Rudolf Dipl Chem Dr Hurnaus, Richard Dr Reichl, Tetrahydro azepinoquinolines - with anorexigenic, hypolipaemic, hypoglycaemic, antidepressant and antiallergic activitys ,(1973)
Yukinobu Iketani, Hiroshi Mihashi, Iwao Sakakibara, Shunji Sato, Novel lignans and protease inhibitor using lignans or phenylpropanes as active ingredient ,(1988)