Treatment of Inflammatory Cardiomyopathy with Corticosteroids

作者: U. Kühl , H.-P. Schultheiss

DOI: 10.1007/978-3-642-60463-8_25

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摘要: Dilated cardiomyopathy (DCM) is defined as a heart disease of unknown cause with enlargement and impaired contraction the left or both ventricles. It may be idiopathic, familial/genetic, viral and/or immune, alcoholic/toxic, associated recognized cardiovascular diseases in which degree myocardial dysfunction not sufficiently explained by causative [1]. Recent clinical experimental data have suggested coincidental relationship myocarditis [2].Viral persistence has been documented chronic failure [3–7]. While acute phase tissue destruction caused direct cytotoxic effect virus, extent damage depression cardiac function state depends on virally induced humoral cellular immune processes. These one hand limit further expansion destructive process, but other they themselves ongoing injury to myocardium.

参考文章(25)
FJ Schoen, JT Fallon, ME Billingham, WD Edwards, EG Olsen, SM Factor, HT Aretz, Jr Jj Fenoglio, Myocarditis. A histopathologic definition and classification. The American journal of cardiovascular pathology. ,vol. 1, pp. 3- 14 ,(1987)
U. Kühl, M. Noutsias, B. Seeberg, M. Schannwell, L.B. Welp, H.-P. Schultheiss, Chronic inflammation in the myocardium of patients with clinically suspected dilated cardiomyopathy Journal of Cardiac Failure. ,vol. 1, pp. 13- 25 ,(1994) , 10.1016/1071-9164(94)90004-3
Ricky D. Latham, John P. Mulrow, Renu Virmani, Max Robinowitz, Joe M. Moody, Recently diagnosed idiopathic dilated cardiomyopathy: Incidence of myocarditis and efficacy of prednisone therapy American Heart Journal. ,vol. 117, pp. 876- 882 ,(1989) , 10.1016/0002-8703(89)90626-1
Jay W. Mason, Margaret E. Billingham, Donald R. Ricci, Treatment of acute inflammatory myocarditis assisted by endomyocardial biopsy American Journal of Cardiology. ,vol. 45, pp. 1037- 1044 ,(1980) , 10.1016/0002-9149(80)90174-5
ARTHUR J. HAUCK, DEBRA L. KEARNEY, WILLIAM D. EDWARDS, Evaluation of Postmortem Endomyocardial Biopsy Specimens From 38 Patients With Lymphocytic Myocarditis: Implications for Role of Sampling Error Mayo Clinic Proceedings. ,vol. 64, pp. 1235- 1245 ,(1989) , 10.1016/S0025-6196(12)61286-5
R. Kandolf, D. Ameis, P. Kirschner, A. Canu, P. H. Hofschneider, In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 6272- 6276 ,(1987) , 10.1073/PNAS.84.17.6272
Joseph E. Parrillo, Robert E. Cunnion, Stephen E. Epstein, Margaret M. Parker, Anthony F. Suffredini, Matthew Brenner, Gary L. Schaer, Sebastian T. Palmeri, Richard O. Cannon, David Alling, Janet T. Wittes, Victor J. Ferrans, E. Rene Rodriguez, Anthony S. Fauci, A Prospective, Randomized, Controlled Trial of Prednisone for Dilated Cardiomyopathy New England Journal of Medicine. ,vol. 321, pp. 1061- 1068 ,(1989) , 10.1056/NEJM198910193211601
R. Kandolf, P. H. Hofschneider, Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: full-length reverse-transcribed recombinant cDNA generates infectious virus in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 82, pp. 4818- 4822 ,(1985) , 10.1073/PNAS.82.14.4818