Anti-Hypertensive Prescription and Cost Patterns in an Outpatient Department of a Teaching Hospital in Lagos State Nigeria
作者： Akin Osibogun , Tochi Joy Okwor
关键词:
摘要: Introduction: Hypertension is a public health problem with a high prevalence in Nigeria. The cost of prescription medications thought to be barrier for many patients access the healthcare they need. This study was aimed at identifying associated co-morbid conditions, the prescribing patterns and of prescription the treatment hypertension an outpatient clinic Lagos University Teaching Hospital. Materials Methods: A cross sectional carried out. A total 147 prescriptions were obtained from case notes patients treated LUTH outpatient department between February 2012 August 2012. For each prescription, the number drugs, class combinations antihypertensives recorded. The monthly 30-day anti-hypertensive supply based on recommended daily dose calculated. Results: mean age 54(+/-14) years prescriptions, 77(52.4%) females 70(47.6%) was for males. systolic blood pressure 141.6 mmHg (+/-20.5SD) mean diastolic 86.5 (+/-13.3SD). Of 112(76.2%) with co-morbidities. frequency various classes anti hypertensives are; diuretics 117(79.6%), angiotensin receptor blockers 78(53.1%), converting enzyme inhibitors 65(44.2%), calcium channel blockers 65 (44.2%) beta blockers 54(36.7%) centrally acting agents 12(8.2%). Average per month was =N=6611.47 (US$44). There statistically significant association between co morbid conditions and high 73.7% those diabetes 63.2% those with renal disease having within group (p
sci-hub.st 参考文章(18)
A Q Adigun, D A Ishola, A O Akintomide, A A L Ajayi, Shifting trends in the pharmacologic treatment of hypertension in a Nigerian tertiary hospital: a real-world evaluation of the efficacy, safety, rationality and pharmaco-economics of old and newer antihypertensive drugs Journal of Human Hypertension. ,vol. 17, pp. 277- 285 ,(2003) , 10.1038/SJ.JHH.1001538
C O Amira, N U Okubadejo, Antihypertensive pharmacotherapy in a developing economy: pattern, acquisition costs and conformity to international guidelines in a tertiary-care setting Journal of Human Hypertension. ,vol. 20, pp. 894- 897 ,(2006) , 10.1038/SJ.JHH.1002080
Obinna Ikechukwu Ekwunife, Patrick Obinna Udeogaranya, Izuchukwu Loveth Nwatu, Prevalence, awareness, treatment and control of hypertension in a nigerian population Health. ,vol. 02, pp. 731- 735 ,(2010) , 10.4236/HEALTH.2010.27111
WO Erhun, G Olayiwola, EO Agbani, NS Omotoso, Prevalence of hypertension in a University Community in South West Nigeria African Journal of Biomedical Research. ,vol. 8, pp. 15- 19 ,(2006) , 10.4314/AJBR.V8I1.35753
Pang-Hsiang Liu, Jung-Der Wang, Antihypertensive medication prescription patterns and time trends for newly-diagnosed uncomplicated hypertension patients in Taiwan BMC Health Services Research. ,vol. 8, pp. 133- 133 ,(2008) , 10.1186/1472-6963-8-133
SA Adebisi, Ek Oghagbon, AK Jimoh, Glycated haemoglobin and associated variables in diabetics: Ilorin experience. West African journal of medicine. ,vol. 22, pp. 318- 320 ,(2004) , 10.4314/WAJM.V22I4.28055
H.V. Hogerzeil, Bimo, D. Ross-Degnan, R.O. Laing, D. Ofori-Adjei, B. Santoso, A.K. Azad Chowdhury, A.M. Das, K.K. Kafle, A.F.B. Mabadeje, A.Y. Massele, Field tests for rational drug use in twelve developing countries The Lancet. ,vol. 342, pp. 1408- 1410 ,(1993) , 10.1016/0140-6736(93)92760-Q
Patricia M Kearney, Megan Whelton, Kristi Reynolds, Paul Muntner, Paul K Whelton, Jiang He, Global burden of hypertension: analysis of worldwide data The Lancet. ,vol. 365, pp. 217- 223 ,(2005) , 10.1016/S0140-6736(05)17741-1
Jun Ma, Ky-Van Lee, Randall S. Stafford, Changes in Antihypertensive Prescribing During US Outpatient Visits for Uncomplicated Hypertension Between 1993 and 2004 Hypertension. ,vol. 48, pp. 846- 852 ,(2006) , 10.1161/01.HYP.0000240931.90917.0C
S HALL, A user's guide to selecting a comorbidity index for clinical research Journal of Clinical Epidemiology. ,vol. 59, pp. 849- 855 ,(2006) , 10.1016/J.JCLINEPI.2005.11.013