Results in Children of Acute Lymphoid Leukemia: Protocol ICIG-ALL 9 Consisting of Chemotherapy for Only 9 Months Followed by Active Immunotherapy

作者: G. Mathe , F. Vassal , L. Schwarzenberg , M. A. Gil , M. Delgado

DOI: 10.1007/978-3-642-81174-6_11

关键词:

摘要: In 1962, we started a controlled study (the principle of which was based on our experimental data) [19] to compare active systemic immunotherapy (AI) with no treatment for patients acute lymphoid leukemia (ALL) after stopping their rerhission chemotherapy. The difference in remission duration and survival favor AI became significant so rapidly [21] that, obvious ethical juridical reasons, were not authorized introduce more than the 30 already trial, nor perform another trial controls left without treatment. We recently published two critical discussions this [20, 22].

参考文章(32)
RM Heyn, P Joo, M Karon, M Nesbit, N Shore, N Breslow, J Weiner, A Reed, D Hammond, BCG in the treatment of acute lymphocytic leukemia Blood. ,vol. 46, pp. 431- 442 ,(1975) , 10.1182/BLOOD.V46.3.431.431
A. Vessereau, D. Schwartz, R. Flamant, J. Lellouch, L'essai thérapeutique chez l'homme Revue de l'Institut International de Statistique / Review of the International Statistical Institute. ,vol. 38, pp. 421- ,(1970) , 10.2307/1402215
Georges Mathé, Cancer active immunotherapy. Immunoprophylaxis and immunorestoration. An introduction. Recent results in cancer research. ,vol. 55, pp. 1- 402 ,(1976)
G. K. Smith, E. D. Smith, Selection for Treatment in Spina Bifida Cystica BMJ. ,vol. 4, pp. 189- 197 ,(1973) , 10.1136/BMJ.4.5886.189
G. Mathé, M. Kamel, M. Dezfulian, O. Halle-Pannenko, C. Bourut, An Experimental Screening for “Systemic Adjuvants of Immunity” Applicable in Cancer Immunotherapy Cancer Research. ,vol. 33, pp. 1987- 1997 ,(1973) , 10.1007/978-3-642-49284-6_21
Georges Mathé, Henry Rappaport, GT O'Conor, Humberto Torloni, World Health Organization, None, Histological and cytological typing of neoplastic diseases of haematopoietic and lymphoid tissues ,(1976)
L. Schwarzenberg, M.C. Simmler, J.L. Pico, Human toxicology of BCG applied in cancer immunotherapy Cancer Immunology, Immunotherapy. ,vol. 1, pp. 69- 76 ,(1976) , 10.1007/BF00205297
MartinF. Mckneally, CaroleM. Maver, HarveyW. Kausel, INTRAPLEURAL B.C.G. IMMUNOSTIMULATION IN LUNG CANCER The Lancet. ,vol. 309, pp. 593- ,(1977) , 10.1016/S0140-6736(77)92015-3