Cytotoxic and genotoxic potential of tannery waste contaminated soils
作者： Farhana Masood , Abdul Malik
DOI: 10.1016/J.SCITOTENV.2012.11.049
关键词:
摘要: Soil samples from agricultural fields in the vicinity of industrial area Jajmau, Kanpur (India) were collected and found to be heavily contaminated with various toxic heavy metals. GC-MS analysis revealed presence organic compounds mainly phthalates soils. Samples extracted using dichloromethane (DCM) hexane solvents, extracts assayed for genotoxic potential three different bioassays namely Ames Salmonella/mammalian microsome test, DNA repair defective Escherichia coli K-12 mutants Allium cepa chromosomal aberration assay. TA98 was most sensitive strain all soil tested. The highest mutagenic observed DCM as compared each Salmonella typhimurium. exhibited maximum damage cells at a dose 40 μl extracts/ml culture after 6-h treatment. survival 23% polA, 40% lexA 53% recA when treated extract site I. In A. assay, test concentrations (5-100%) affected mitotic index dose-dependent manner several types abnormalities stages treatments: C-mitosis, anaphase bridges, laggards, binucleated cells, stickiness, broken unequal distributions chromosomes stage cell division. is accumulating large number pollutants result wastewater irrigation this practice accumulation has an adverse impact on health.
harvard.edu
elsevier.com
sci-hub.se 参考文章(36)
Jean-Paul Rila, Adolf Eisentraeger, Application of Bioassays for Risk Characterisation and Remediation Control of Soils Polluted with Nitroaromatics and PAHs Water Air and Soil Pollution. ,vol. 148, pp. 223- 242 ,(2003) , 10.1023/A:1025486625206
I.C. Eom, C. Rast, A.M. Veber, P. Vasseur, Ecotoxicity of a polycyclic aromatic hydrocarbon (PAH)-contaminated soil. Ecotoxicology and Environmental Safety. ,vol. 67, pp. 190- 205 ,(2007) , 10.1016/J.ECOENV.2006.12.020
T J Hughes, L D Claxton, L Brooks, S Warren, R Brenner, F Kremer, Genotoxicity of bioremediated soils from the Reilly Tar site, St. Louis Park, Minnesota. Environmental Health Perspectives. ,vol. 106, pp. 1427- 1433 ,(1998) , 10.1289/EHP.98106S61427
Bruce N. Ames, Joyce McCann, Edith Yamasaki, Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test Mutation Research. ,vol. 31, pp. 347- 364 ,(1975) , 10.1016/0165-1161(75)90046-1
Mohd Ikram Ansari, Abdul Malik, Genotoxicity of agricultural soils in the vicinity of industrial area. Mutation Research-genetic Toxicology and Environmental Mutagenesis. ,vol. 673, pp. 124- 132 ,(2009) , 10.1016/J.MRGENTOX.2008.12.006
M Costa, DNA-protein complexes induced by chromate and other carcinogens. Environmental Health Perspectives. ,vol. 92, pp. 45- 52 ,(1991) , 10.1289/EHP.919245
Reshma Anjum, Abdul Malik, Mutagenicity assessment of contaminated soil in the vicinity of industrial area Environmental Monitoring and Assessment. ,vol. 184, pp. 3013- 3026 ,(2012) , 10.1007/S10661-011-2167-7
Richard D'Ari, The SOS system Biochimie. ,vol. 67, pp. 343- 347 ,(1985) , 10.1016/S0300-9084(85)80077-8
Dorothy M. Maron, Bruce N. Ames, REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST Mutation Research. ,vol. 113, pp. 173- 215 ,(1983) , 10.1016/0165-1161(83)90010-9
María Dolores Fernández, Ekain Cagigal, María Milagrosa Vega, Arantzazu Urzelai, Mar Babín, Javier Pro, José Vicente Tarazona, Ecological risk assessment of contaminated soils through direct toxicity assessment. Ecotoxicology and Environmental Safety. ,vol. 62, pp. 174- 184 ,(2005) , 10.1016/J.ECOENV.2004.11.013