作者: Xenofon Strakosas , Michele Sessolo , Adel Hama , Jonathan Rivnay , Eleni Stavrinidou
DOI: 10.1039/C3TB21491E
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摘要: For the majority of biosensors or biomedical devices, immobilization biorecognition element is a critical step for device function. To achieve longer lifetime devices and controllable functionalization, covalent immobilisation techniques are preferred over passive adhesion electrostatic interactions. The rapidly emerging field organic bioelectronics uses conducting polymers (or small molecules) as active materials transduction biological signal to an electronic one. While number have been utilized entrap functionalize deposited by electro- vapor phase polymerization, functionalization solution processed films, essential realizing low cost high throughput fabrication, has not thoroughly investigated. In this study we show versatile biofunctionalization technique processable polymer poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonate) PEDOT:PSS, which commercially available material, record conductivity. Addition poly(vinyl alcohol) (PVA) into PEDOT:PSS provides handle subsequent silanization well-characterised silane reagent, allowing linkage moieties onto films. We homogenous large-scale polypeptides proteins, well maintenance functionalities proteins. addition, no deleterious effects noted on ionic transport properties films due incorporation PVA.