The seroepidemiology of Helicobacter pylori infection in Australia

摘要: Summary Background Infection with Helicobacter pylori is common worldwide and a significant cause of upper gastrointestinal disease. Prevalence this infection varies in different population groups internationally. Because the invasiveness specimen collection for bacteriologic diagnosis expense tests such as labeled urea breath tests, serology most feasible means determining epidemiology H. . The aim study was to describe seroepidemiology Australia. Methods -specific ELISA presence IgG antibodies performed on representative sample 2413 sera from Australia 2002, using validated serosurveillance methods. Results overall seroprevalence 15.1% no statistical difference between genders. Seropositivity rates increased progressively age, ranging 4.0% 1–4-year-olds 23.3% 50–59-year-olds. Conclusions prevalence lower than reported other developed countries, at 15.4%. This provides important baseline measurements future preventive measures including vaccine research development. Further studies determine subgroups higher risk may help target more susceptible populations.