Early versus Delayed Refeeding for Children with Acute Diarrhoea

摘要: Background Acute diarrhoea is one of the principal causes morbidity and mortality among children in low-income countries.  The cornerstone treatment oral rehydration therapy dietary management.  However, there a lack data studies on both timing type feeding that should be adopted during course illness. Objectives To compare efficacy safety early late reintroduction with acute diarrhoea. Search methods In May 2011, we searched Cochrane Infectious Diseases Group Specialized Register, CENTRAL (The Library Issue 1), MEDLINE, EMBASE, LILACS, mRCT. We also contacted researchers organizations, reference lists. Selection criteria Randomized controlled trials versus refeeding less than 10 years old diarrhoea.  Early was defined as within 12 hours start more after rehydration.  Data collection analysis Two authors independently assessed search results risk bias, extracted data. present ratios for dichotomous outcomes mean differences continuous outcomes. combined using meta-analysis when heterogeneity not substantial. Main results Twelve involving 1283 participants wereincluded; 1226 were used analysis (724 group 502 group). Nine described their allocation sequence, but only two concealed allocation. One trial reported single-blinding did clearly identify person who blinded. meant intake or immediately rehydration, while 20 to 48 rehydration. Significant noted duration diarrhoea. There no significant difference between groups number needed unscheduled intravenous fluids (six 813 participants), experienced episodes vomiting (five 466 developed persistent (four 522 participants). length hospital stay similar (two 246 participants). Authors' conclusions There evidence increases fluid use, vomiting, development No conclusion could made regarding