Towards an animal model of callousness.

摘要: Callous-unemotional traits - the insensitivity to other's welfare and well-being are characterized by a lack of empathy. They characteristic psychopathy can be found in other anti-social disorders, such as conduct disorder. Because increasing prevalence disorders rising societal costs violence aggression, it is great importance elucidate psychological physiological mechanisms underlying callousness search for pharmacological treatments. One promising avenue create relevant animal model explore neural bases callousness. Here, we review recent advances rodent models pro-social choice that could applied probe absence pro-sociality proxy callous behavior, provide future directions exploration substrates