Cranial base reconstruction after transsphenoidal surgery with bioabsorbable implants.

摘要: Objective Reconstruction of the cranial base is often necessary after transsphenoidal surgery to prevent occurrence cerebrospinal fluid rhinorrhea and maintain anatomic integrity. In most cases, sellar packing (fat, muscle, gelatin sponge) may be supported by bone or cartilage harvested at time surgery. The use synthetic material, however, becomes desirable in cases which an autograft not available. Low-molecular-weight polylactide implants serve as effective alternative because they are immunologically inert, magnetic resonance imaging-compatible, easily contoured custom-fit a defect. Methods results MacroSorb (MacroPore, San Diego, CA) absorbable plates made from amorphous 70:30 poly (L-lactide-co-D,L-lactide) polymers. Implants malleable temperatures 70 degrees C solidify room body temperature; resorbed 18 months. Conclusion Polylactide polymer adjuncts when reconstruction endogenous osseous cartilaginous graft unavailable.