作者: Richard E. Kuntz , Anna N.A. Tosteson , Aaron D. Berman , Lee Goldman , Paul C. Gordon
DOI: 10.1056/NEJM199107043250104
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摘要: Abstract Background. Balloon aortic valvuloplasty was developed as an alternative to aortic-valve replacement in selected elderly patients with stenosis. The use of this procedure is limited, however, by a high incidence re-Stenosis. Methods. Between December 1985 and April 1989, performed 205 patients. We evaluated 40 demographic hemodynamic variables univariate predictors event-free survival Cox regression analysis identified independent eventfree stepwise multivariate analysis. Results. Early results indicated decrease the peak transaortic-valve pressure gradient from 67±28 33±15 mm Hg after increase area 0.6±0.2 0.9±0.3 cm2 (P<0.001 for both comparisons). rate (defined without recurrent symptoms, repeated valvuloplasty, or replacement) 18 percent over mean (±SD) follow-up period 24±12 months (range, 1 t...