Current Treatment of Unresectable Lung Cancer

摘要: The treatment of choice for most cases non-small-cell lung cancer is surgical resection; however, which patients with stage IIIA disease are candidates debatable. For many or IIIB disease, the preferred modality thoracic radiotherapy. In several randomized prospective trials, addition chemotherapy to radiotherapy produced a significant but clinically small survival advantage over alone. IV cancer, no curative "standard therapy" available. Accordingly, offered investigational agents in phase I II clinical trials. Small-cell has 60 90% rate initial response available chemotherapeutic agents. Patients limited generally given combination and radiotherapy, approximately 50% whom have complete remission. extensive (spread beyond one radiation port) also high chemotherapy, only 20 40% remission few survive 5 years. New being tested previously untreated small-cell cancer. Promising new studied Currently, 1% United States enrolled Primary-care physicians urged encourage their consider participation approved trials at reputable medical centers, an effort discover new, effective novel mechanisms action. Information about such studies through Physician Desk Query (PDQ) hotline (1-800-4-CANCER).