Body composition changes differ by gender in stomach, colorectal, and biliary cancer patients with cachexia: Results from a pilot study.
作者： Saunjoo L. Yoon , Oliver Grundmann , Joseph J. Williams , Lucio Gordan , Thomas J. George
DOI: 10.1002/CAM4.1665
关键词:
摘要: Few studies have examined the possibility that cachexia may affect men and women differently. This pilot study assessed gender differences in body composition stomach, colorectal, biliary cancer patients with cachexia. A sample of 38 participants (Female: Male = 17:21, mean age 57.4 years) were included if they undergoing chemotherapy experienced weight loss 5% or more over a 6-month period. Bioelectrical impedance analysis (BIA) was applied to measure composition. Phase angle (PA) levels extra-/intracellular water (ECW; ICW) determined. Data analyzed first by then compared age- gender-matched healthy controls from NHANES-III dataset. PA lower (P < .01) both genders controls, female male .03). also had ICW (r .98, P .01). For patients, negatively correlated .897, ECW/ICW ratio highly .969 for men, r .639 women) increased patients. changes are gender-specific GI cancer. ratios be suitable surrogate markers cell health status.
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