摘要: Gout is the most prevalent inflammatory arthritis in men. The findings of several epidemiological studies from a diverse range countries suggest that prevalence gout has risen over last few decades. Whilst incidence data are scarce, US suggests also rising. Evidence prospective confirmed dietary factors (animal purines, alcohol and fructose), obesity, metabolic syndrome, hypertension, diuretic use, chronic kidney disease as clinically relevant risk for hyperuricemia gout. Low-fat dairy products, coffee, vitamin C appear to have protective effect. Further required examine other proposed hyperuricaemia such use β-blockers angiotension-II receptor antagonists (other than losartan), obstructive sleep apnoea, osteoarthritis, putative calcium-channel blockers losartan.
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