Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies.

摘要: BACKGROUND Recurrent acute pancreatitis (RAP) may be a presenting feature of and an indication for resection pancreatic cysts, including intra-ductal papillary mucinous neoplasm (IPMN). Few data are available regarding the prevalence malignancy post-operative RAP in this population. AIM To study role to help prevent analyze if presentation as would predictor malignancy. METHODS This retrospective assessed 172 patients who underwent surgical cystic neoplasms at university hospital between 2002 2016. The preoperative high-risk cyst features, neoplasia was compared with without RAP. identify cause pancreatitis, all had detailed history alcohol, smoking, medications obtained, cross-sectional imaging (contrast-enhanced computed tomography/magnetic resonance imaging) endoscopic ultrasound look gallstone etiology other structural causes pancreatitis. incidence post-resection primary outcome. RESULTS IPMN accounted 101 cases (58.7%) {[branch duct (BD) 59 (34.3%), main (MD) 42] (24.4%)}. Twenty-nine (16.9%) presented (mean 2.2 episodes): 15 BD-IPMN, 8 MD-IPMN, 5 1 serous neoplasm. Malignancy similar among those vs [6/29 (20.7%) 24/143 (16.8%)] [6/23 (26.1%) 23/78 (29.5%)], although tended higher [5/15 (33.3%) 3/44 (6.8%), P = 0.04]. At mean follow-up 7.2 years, (3.4%) patient episodes before after surgery were 3.4 0.02 (P < 0.0001). CONCLUSION not increased have In addition, specific charac-teristics clearly associated markedly decreased almost following resection.