摘要: Characterizing the patterns of genetic variation in an organism provides fundamental insight into evolutionary history and defines scope nature studies that must be designed to correlate genotype phenotype. Given pre-eminent role inbred mouse biomedical research, considerable effort has been undertaken recent years describe more fully amount among numerous strains mice are widest use. Here, we discuss have contributed emerging understanding unique found how they arisen through a combination natural evolution human-directed breeding. These preliminary results ramifications for research complex traits basis development future resources.
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