Pancreatic enzymes in chronic renal failure and transplant patients.

作者: Alberto Notarbartolo , Antonio Carroccio , Daniela Di Martino , Giuseppe Montalto , Maurizio Soresi

DOI: 10.1007/BF02924359

关键词:

摘要: The aim of the present study was to determine frequency and degree elevated serum levels Total Amylase (TA), Pancreatic (PA), Lipase (L) activity in patients with chronic renal failure (CRF) on conservative therapy; CRF periodical hemodialysis (HD); transplant (RT) a control Group (C). Mean values were significantly higher all groups than C for TA (p < 0.005), PA 0.0001) L 0.0001). A statistically significant correlation found between vs creatininemia patients, but only up certain level (creatininemia 6 mg %) 0.03 p 0.05), above which there no correlation. enzyme most frequently over maximum normal limit PA, both total group (51%), (65%), RT (55%); few had two times limits: 15% CRF, 14% is hemodialysis, 10% groups, respectively. These results suggest that increase pancreatic during pathology slight occurs. It possible these together excretion impairment could also be some subclinical damage; its genesis depend pharmacological treatment used (diuretics, immunosuppressive drugs) commonly adopted pathologies.

参考文章(17)
Vicki L. Royse, Panc reatic Enzymes in Chronic Renal Failure Archives of Internal Medicine. ,vol. 147, pp. 537- 539 ,(1987) , 10.1001/ARCHINTE.1987.00370030141028
J. EDWARD BERK, Amylase and lsoamylase Activities in Renal Insufficiency Annals of Internal Medicine. ,vol. 90, pp. 351- 353 ,(1979) , 10.7326/0003-4819-90-3-351
George L. Bailey, Alterations in Serum Enzymes in Chronic Renal Failure JAMA: The Journal of the American Medical Association. ,vol. 213, pp. 2263- 2265 ,(1970) , 10.1001/JAMA.1970.03170390053014
N.D. Vaziri, B. Dure-Smith, R. Miller, M. Mirahmadi, Pancreatic pathology in chronic dialysis patients--an autopsy study of 78 cases. Nephron. ,vol. 46, pp. 347- 349 ,(1987) , 10.1159/000184387
Morrell Michael Avram, High Prevalence of Pancreatic Disease in Chronic Renal Failure Nephron. ,vol. 18, pp. 68- 71 ,(1977) , 10.1159/000180768
Maurizio R. Averna, Carlo M. Barbagallo, Antonio Galione, Antonio Carroccio, Mirella Labisi, Giuseppina Marino, Giuseppe Montalto, Alberto Notarbartolo, Serum apolipoprotein profile of hypertriglyceridemic patients with chronic renal failure on hemodialysis: A comparison with type IV hyperlipoproteinemic patients Metabolism. ,vol. 38, pp. 601- 602 ,(1989) , 10.1016/0026-0495(89)90093-0
J Schönebeck, M Söderberg, Serum Amylase in Renal Failure Scandinavian Journal of Urology and Nephrology. ,vol. 5, pp. 257- 262 ,(1971) , 10.3109/00365597109133609
J B Keogh, K F McGeeney, M I Drury, T B Counihan, M D O'Donnell, Renal clearance of pancreatic and salivary amylase relative to creatinine in patients with chronic renal insufficiency. Gut. ,vol. 19, pp. 1125- 1130 ,(1978) , 10.1136/GUT.19.12.1125
N D Vaziri, S Radaht, D Chang, A Malekpour, Pancreatic enzymes in patients with end-stage renal disease maintained on hemodialysis. The American Journal of Gastroenterology. ,vol. 83, pp. 410- 412 ,(1988)