Dietary fat and breast cancer risk revisited: a meta-analysis of the published literature
作者： L J Martin , S Minkin , N F Boyd , J Stone , K N Vogt
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摘要: Animal experiments and human ecological studies suggest that dietary fat intake is associated with a risk of breast cancer, but individual-based have given contradictory results. We carried out meta-analysis this association to include all papers published up July 2003. Case–control cohort examined the fat, or fat-containing foods, cancer were identified. A total 45 estimates for obtained. Descriptive data from each study extracted an estimate relative its 95% confidence interval (CI), analysed using random effects model DerSimonian Laird. The summary risk, comparing highest lowest levels was 1.13 (95% CI: 1.03–1.25). Cohort (N=14) had 1.11 0.99–1.25) case–control (N=31) 1.14 CI 0.99–1.32). Significant risks also found saturated (RR, 1.19; 1.06–1.35) meat 1.17; 1.06–1.29). Combined intake, indicate between higher intakes increased cancer. gave similar
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