Low serum concentrations of insulin-like growth factor-I in children with active Crohn disease: effect of enteral nutritional support and glutamine supplementation.
作者： A. K. Akobeng , P. E. Clayton , V. Miller , C. M. Hall , A. G. Thomas
DOI: 10.1080/003655202762671521
关键词:
摘要: Background: Impaired growth is a frequent problem in childhood Crohn disease. Low serum concentrations of insulin-like factor-I (IGF-I), an important marker nutritional status and linear growth, have been described children with This study tested the hypotheses that enteral support glutamine supplementation would be associated improvements IGF-I levels Methods: In double-blind randomized controlled study, 15 active disease (8 boys, 7 girls; mean age 11.3 years, range 6.8-15.7) were assigned to receive 4-week course either standard low polymeric diet (4% amino acid content) (Group S, n = 8) or isocaloric, isonitrogenous, glutamine-enriched (42% G, 7). Serum was measured by radioimmunoassay method at 0 4 weeks converted deviation scores (SDS). Weight SDS, height weight-for-height, height-for-ag...
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