Volumetric MRI of the lungs during forced expiration

摘要: Purpose Lung function is typically characterized by spirometer measurements, which do not offer spatially specific information. Imaging during exhalation provides spatial information but challenging due to large movement over a short time. The purpose of this work provide solution lung imaging forced expiration using accelerated magnetic resonance imaging. method uses radial golden angle stack-of-stars gradient echo acquisition and compressed sensing reconstruction. Methods A technique for dynamic three-dimensional the lungs from highly undersampled data developed tested on six subjects. This takes advantage image sparsity, both temporally, including use reference frames called bookends. Sparsity, with respect total variation, residual bookends, enables reconstruction an extremely limited amount data. Results Dynamic images can be captured at sub-150 ms temporal resolution, only three (or less) acquired lines per slice timepoint. have resolution mm. Lung volume calculations based segmentation are compared those simultaneously measurements. Conclusion Dynamic made possible Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.