Growth Responses of a Sulfonamide-requiring Mutant Strain of Neurospora1

摘要: A mutant strain of Neurospora crassa has appeared in which the antagonistic roles p-aminobenzoic acid and sulfonamides have been reversed to a considerable extent. Optimal growth this occurs only presence sulfonamides. Conversely, is potent fungistatic agent for under certain conditions. To say that sulfanilamide become an essential metabolite inhibiting analog would be oversimplify altered physiology strain. It will shown that, strain, both are growth, each acts as other. These interrelations further complicated by effect temperature on need sulfonamides, inhibition acid. The present report deals exclusively with responses temperature, At time nothing definite known physiological role