Identification of GATA3 as a Breast Cancer Prognostic Marker by Global Gene Expression Meta-analysis

作者: Rohit Mehra , Sooryanarayana Varambally , Lei Ding , Ronglai Shen , Michael S. Sabel

DOI: 10.1158/0008-5472.CAN-05-2495

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摘要: … in detail somatic mutations of GATA3 in five ER-α-… MCF-7 and suggested that loss of GATA3 may contribute to tumorigenesis in ER-positive breast cancers. Here, we show that GATA3 …

参考文章(19)
Ronglai Shen, Debashis Ghosh, Arul M Chinnaiyan, Prognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray data BMC Genomics. ,vol. 5, pp. 94- 94 ,(2004) , 10.1186/1471-2164-5-94
T Barrette, A Pandey, AM Chinnaiyan, ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform Neoplasia. ,vol. 6, pp. 1- 6 ,(2004) , 10.1016/S1476-5586(04)80047-2
Jerry Usary, Victor Llaca, Gamze Karaca, Shafaq Presswala, Mehmet Karaca, Xiaping He, Anita Langerød, Rolf Kåresen, Daniel S Oh, Lynn G Dressler, Per E Lønning, Robert L Strausberg, Stephen Chanock, Anne-Lise Børresen-Dale, Charles M Perou, Mutation of GATA3 in human breast tumors Oncogene. ,vol. 23, pp. 7669- 7678 ,(2004) , 10.1038/SJ.ONC.1207966
C. Sotiriou, S.-Y. Neo, L. M. McShane, E. L. Korn, P. M. Long, A. Jazaeri, P. Martiat, S. B. Fox, A. L. Harris, E. T. Liu, Breast cancer classification and prognosis based on gene expression profiles from a population-based study Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 10393- 10398 ,(2003) , 10.1073/PNAS.1732912100
C.W. ELSTON, I.O. ELLIS, Pathology and breast screening. Histopathology. ,vol. 16, pp. 109- 118 ,(2007) , 10.1111/J.1365-2559.1990.TB01078.X
Renee V. Hoch, Devon A. Thompson, Robin J. Baker, Ronald J. Weigel, GATA-3 is expressed in association with estrogen receptor in breast cancer. International Journal of Cancer. ,vol. 84, pp. 122- 128 ,(1999) , 10.1002/(SICI)1097-0215(19990420)84:2<122::AID-IJC5>3.0.CO;2-S
Charles M. Perou, Therese Sørlie, Michael B. Eisen, Matt van de Rijn, Stefanie S. Jeffrey, Christian A. Rees, Jonathan R. Pollack, Douglas T. Ross, Hilde Johnsen, Lars A. Akslen, Øystein Fluge, Alexander Pergamenschikov, Cheryl Williams, Shirley X. Zhu, Per E. Lønning, Anne-Lise Børresen-Dale, Patrick O. Brown, David Botstein, Molecular portraits of human breast tumours Nature. ,vol. 406, pp. 747- 752 ,(2000) , 10.1038/35021093
M. Andrew Nesbit, Michael R. Bowl, Brian Harding, Asif Ali, Alejandro Ayala, Carol Crowe, Angus Dobbie, Geeta Hampson, Ian Holdaway, Michael A. Levine, Robert McWilliams, Susan Rigden, Julian Sampson, Andrew J. Williams, Rajesh V. Thakker, Characterization of GATA3 Mutations in the Hypoparathyroidism, Deafness, and Renal Dysplasia (HDR) Syndrome Journal of Biological Chemistry. ,vol. 279, pp. 22624- 22634 ,(2004) , 10.1074/JBC.M401797200
C. G. Kleer, Q. Cao, S. Varambally, R. Shen, I. Ota, S. A. Tomlins, D. Ghosh, R. G. A. B. Sewalt, A. P. Otte, D. F. Hayes, M. S. Sabel, D. Livant, S. J. Weiss, M. A. Rubin, A. M. Chinnaiyan, EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 11606- 11611 ,(2003) , 10.1073/PNAS.1933744100