Lymphocyte Blastogenesis to Human Leukemia Cells and Their Relationship to Serum Factors, Immunocompetence, and Prognosis

摘要: Lymphocyte blastogenic studies to autologous leukemia cells were carried out in 35 patients with adult acute leukemia. The effects of serum on this response and correlation general immunocompetence studied. Twenty-five had positive blastogenesis. Nine myelogenous complete or partial abrogation serum. Five facilitation the compared allogeneic Patients a more vigorous their than lymphoblastic Although tended correlate vitro cells, only one patient who was unresponsive immunoincompetent. A good prognosis correlated inhibition that by serum, persistently remission.