Antihyperlipidemic activity of chickpea sprouts supplementation in ovariectomy-induced dyslipidemia in rats
作者： MekapoguAlpha Raj , Ch. Srilatha , Kaliki Adilaxmamma , Sagili Harini , EmaniMadan Mohan
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摘要: Background: Phytoestrogens are increasingly becoming popular as alternatives for hormone replacement therapy in postmenopausal condition. Objective: In this study, the antihyperlipidemic effect of chickpea ( Cicer arientum ) sprouts was evaluated ovariectomy-induced dyslipidemia rat model comparison with standard agent atorvastatin. Materials and Methods: A total 24 female adult Wistar rats were divided into four groups that is, Group I - Control; II Ovariectomized (OVX) rats; III OVX + germinated (20% diet) IV atorvastatin (1.2 mg/kg b.wt, p.o. ). Body organ weights, serum, liver lipid profile assessed at end 8 weeks. Results: The results indicated ovariectomy significantly P Conclusions: Germinated seeds showed significant activity, which comparable to Further, improved weights helped reversal histopathological changes suggesting its usefulness
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