Alcohol effects on performance monitoring and adjustment: affect modulation and impairment of evaluative cognitive control.

摘要: Alcohol is known to impair self-regulatory control of behavior, though mechanisms for this effect remain unclear. Here, we tested the hypothesis that alcohol’s reduction negative affect (NA) a key mechanism such impairment. This was by measuring amplitude error-related negativity (ERN), component event-related brain potential (ERP) posited reflect extent which behavioral failures are experienced as distressing, while participants completed laboratory task requiring control. reduced both ERN and error positivity (Pe) components ERP following errors impaired typical posterror adjustment. Structural equation modeling indicated effects alcohol on adjustment were significantly mediated reductions in NA. Effects Pe unrelated adjustment, however. These findings indicate role modulation understanding impairment more generally support theories linking with distress-related response failures.