T2* Magnetic Resonance Imaging Sequences Reflect Brain Tissue Iron Deposition Following Intracerebral Hemorrhage

作者: Gang Wu , Guohua Xi , Ya Hua , Oren Sagher

DOI: 10.1007/S12975-009-0008-6

关键词:

摘要: The purpose of this study is to examine the utility magnetic resonance imaging (MRI) T2* sequences as a measure iron overload in brain following intracerebral hemorrhage (ICH). We examined time course changes around hemorrhages series patients. also performed experiments an animal model ICH, examining along with correlation these histological markers ferric deposition. found that occur increasing intensity and spatial distribution over 3-month period. Experimental ICH rat induces similar changes, correlate tightly MRI after can be used degree brain. sequence may useful interventions aimed at reducing ICH-related injury by

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