Nasobronchial interaction in allergic rhinitis and asthma

作者: Gert-Jan Braunstahl

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摘要: textabstractThe key to the diagnosis lies in taking a good medical history. This rule especially applies allergic rhinitis and asthma. Both diseases have common that they are often underdiagnosedl lack proper treatment. Allergic asthma frequently occur together. Almost 40 % of patients lower airways involvement, whereas more than 80 asthma have concomitant symptoms. The latter percentage gets close 95 when a careful nasal history is taken physical examination performed. Allergic characterized by episodes cough, dyspnea, shortness of breath, chest tightness wheezing, combination with variable bronchoconstriction and/or bronchial hyperresponsiveness (BRR). Mucosal inflammation also considered an important hallmark asthma6. However, the associations between mucosal inflammation clinical parameters, such as variable airflow obstruction BRR, are still controversia. Allergic primarily based on typical sneezing, rhinorrhoea, eye symptoms obstruction. As asthma, atopic status needs be confirme

参考文章(151)
S. Lozewicz, E. Gomez, S. Chalstrey, D. Gatland, R.J. Davies, Time Course of Cellular Infiltration in the Nasal Mucosa during the Immediate Allergic Reaction International Archives of Allergy and Immunology. ,vol. 95, pp. 273- 277 ,(1991) , 10.1159/000235441
Qiu Pin Wang, Estelle Escudier, Françoise Roudot-Thoraval, Issam Abd Al Samad, Roger Peynègre, Andre Coste, Myofibroblast Accumulation Induced by Transforming Growth Factor-β Is Involved in the Pathogenesis of Nasal Polyps Laryngoscope. ,vol. 107, pp. 926- 931 ,(1997) , 10.1097/00005537-199707000-00018
C Doucet, D Brouty-Boyé, C Pottin-Clémenceau, G W Canonica, C Jasmin, B Azzarone, Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. Journal of Clinical Investigation. ,vol. 101, pp. 2129- 2139 ,(1998) , 10.1172/JCI741
H. KLEMENTSSON, M. ANDERSSON, C. R. BAUMGARTEN, P. VENGE, U. PIPKORN, Changes in non‐specific nasal reactivity and eosinophil influx and activation after allergen challenge Clinical & Experimental Allergy. ,vol. 20, pp. 539- 547 ,(1990) , 10.1111/J.1365-2222.1990.TB03147.X
EMANUELE CRIMI, ANTONIO SPANEVELLO, MARGHERITA NERI, PHILIP W. IND, GIOVANNI A. ROSSI, VITO BRUSASCO, Dissociation between Airway Inflammation and Airway Hyperresponsiveness in Allergic Asthma American Journal of Respiratory and Critical Care Medicine. ,vol. 157, pp. 4- 9 ,(1998) , 10.1164/AJRCCM.157.1.9703002
W. J. FOKKENS, T. GODTHELP, A. F. HOLM, H. BLOM, P. G. H. MULDER, Th. M. VROOM, E. RIJNTJES, Dynamics of mast cells in the nasal mucosa of patients with allergic rhinitis and non-allergic controls: a biopsy study. Clinical & Experimental Allergy. ,vol. 22, pp. 701- 710 ,(1992) , 10.1111/J.1365-2222.1992.TB00194.X
Robert M. Naclerio, David Proud, Alkis G. Togias, N. Franklin Adkinson, Deborah A. Meyers, Anne Kagey-Sobotka, Marshall Plaut, Philip S. Norman, Lawrence M. Lichtenstein, Inflammatory Mediators in Late Antigen-Induced Rhinitis New England Journal of Medicine. ,vol. 313, pp. 65- 70 ,(1985) , 10.1056/NEJM198507113130201
E. Helen Ramsdale, Marilyn M. Morris, Robin S. Roberts, Frederick E. Hargreave, Asymptomatic bronchial hyperresponsiveness in rhinitis The Journal of Allergy and Clinical Immunology. ,vol. 75, pp. 573- 577 ,(1985) , 10.1016/0091-6749(85)90032-6
P.J. Barnes, Biochemistry of asthma. Trends in Biochemical Sciences. ,vol. 16, pp. 365- 369 ,(1991) , 10.1016/0968-0004(91)90152-L