作者: Mareen Riedel , Jürgen Brinckmann , Armin Steffen , Stefan Nitsch , Barbara Wollenberg
DOI: 10.1111/DDG.12011
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摘要: Summary Background Silicone gel is one therapeutic approach in the treatment and prevention of excessive scarring. The likely mechanism action hydration tissue. This should lead to reduced angiogenesis capillary blood flow. efficacy still controversial evidence base, insufficient. aim this prospective standardized study investigate silicone preventive scars. Patients Methods Included were 20 patients with costal cartilage harvest. Half a standard chest scar was treated for three months gel. other half served as an internal control. After both sides compared subjectively by visual analog scale objectively elasticity, moisture color measurements. Results Of 19 8 had better subjective result half. In subject, no difference seen. A worse seen 10 out 19. objective measurements showed significant difference. correlation between different results not seen. Conclusions The use caused differences within same (worsening well improvement appearance). Positive effects detectable investigated parameters.