Mechanisms of Drug Interactions I
作者： Angela D. M. Kashuba , Joseph S. Bertino
DOI: 10.1385/1-59259-924-9:013
关键词:
摘要: One hundred and fifty million outpatient prescriptions for antibiotics are dispensed each year in the United States (1). In institutional settings, 25–35% of hospitalized patients receive antibiotic treatment active infections or to prevent (2). Given that represent global sales approximately $20 billion a $370 pharmaceutical market, one can assume many who prescribed also receiving other agents (3). Therefore, potential drug interactions is significant.
springer.com
springerlink.com参考文章(194)
Integrated Cytochrome P450 Reaction Phenotyping: Attempting to Bridge the Gap Between cDNA-expressed Cytochromes P450 and Native Human Liver Microsomes Biochemical Pharmacology. ,vol. 57, pp. 465- 480 ,(1999) , 10.1016/S0006-2952(98)00268-8
Jochem Alsenz, Hans Steffen, Rainer Alex, Active apical secretory efflux of the HIV protease inhibitors saquinavir and ritonavir in Caco-2 cell monolayers. Pharmaceutical Research. ,vol. 15, pp. 423- 428 ,(1998) , 10.1023/A:1011924314899
Douglas W. Burget, Stephen G. Chiverton, Richard H. Hunt, Is there an optimal degree of acid suppression for healing of duodenal ulcers? Gastroenterology. ,vol. 99, pp. 345- 351 ,(1990) , 10.1016/0016-5085(90)91015-X
Andrea Soldner, Uwe Christians, Miki Susanto, Vincent J. Wacher, Jeffrey A. Silverman, Leslie Z. Benet, Grapefruit juice activates P-glycoprotein-mediated drug transport. Pharmaceutical Research. ,vol. 16, pp. 478- 485 ,(1999) , 10.1023/A:1011902625609
Kevin R. Sweeney, Poe‐Hirr Hsyu, Paul Statkevich, David R. Taft, Renal disposition and drug interaction screening of (-)-2'-deoxy-3'-thiacytidine (3TC) in the isolated perfused rat kidney. Pharmaceutical Research. ,vol. 12, pp. 1958- 1963 ,(1995) , 10.1023/A:1016252225013
Akira Tsuji, Ikumi Tamai, Carrier-Mediated Intestinal Transport of Drugs Pharmaceutical Research. ,vol. 13, pp. 963- 977 ,(1996) , 10.1023/A:1016086003070
R I Shader, D J Greenblatt, H Friedman, J M Scavone, Effect of age, body composition, and lipid solubility on benzodiazepine tissue distribution in rats. Drug Research. ,vol. 37, pp. 2- 6 ,(1987)
Herbert L. Bonkovsky, Hans-Peter Hauri, Ueli Marti, Uodolfo Gasser, Urs A. Meyer, Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital. Gastroenterology. ,vol. 88, pp. 458- 467 ,(1985) , 10.1016/0016-5085(85)90507-4
Hiroshi Saitoh, Hiroko Fujisaki, Bruce J. Aungst, Katsumi Miyazaki, Restricted Intestinal Absorption of Some β-Lactam Antibiotics by an Energy-Dependent Efflux System in Rat Intestine Pharmaceutical Research. ,vol. 14, pp. 645- 649 ,(1997) , 10.1023/A:1012113430539
B Krevsky, A Maurer, R S Fisher, D Donahue, L C Knight, D J Sher, J L Urbain, Regional differences in gastric acidity and antacid distribution: is a single pH electrode sufficient? The American Journal of Gastroenterology. ,vol. 92, pp. 263- 270 ,(1997)