Synthesis of spiroindenyl-2-oxindoles by montmorillonite K-10-catalyzed tandem Friedel-Crafts alkenylation/hydroarylation of propargylic alcohols with sterically hindered and electron-rich arenes
作者： Hwa Jung Roh , Da Young Seo , Ji Yeon Ryu , Junseong Lee , Jae Nyoung Kim
DOI: 10.1016/J.TETLET.2017.09.035
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摘要: Abstract Various spiroindenyl-2-oxindoles have been synthesized in a one-pot reaction from isatin-derived propargylic alcohols with sterically hindered and electron-rich arenes such as 2-phenylindole 1,3,5-trimethoxybenzene. The involved montmorillonite K-10-catalyzed tandem Friedel-Crafts alkenylation following hydroarylation of an allene intermediate.
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