作者: S. Appenzeller , F. Cendes , L. T.L. Costallat
DOI: 10.1212/01.WNL.0000144178.32208.4F
关键词:
摘要: Objective: To evaluate the frequency and risk factors of epileptic seizures in a large cohort patients with systemic lupus erythematosus (SLE). Methods: Five hundred nineteen consecutive SLE were studied, follow-up ranging from 4 to 7.8 years. The type associated acute recurrent determined. Results: Sixty (11.6%) identified. Epileptic occurred at onset symptoms 19 (31.6%) after 41 60 (68.3%) patients. Fifty-three (88.3%) had symptomatic seizures, 7 (11.7%) seizures. Variables stroke ( p = 0.0004) antiphospholipid antibodies 0.0013). during related nephritis 0.001), 0.005), disease 0.00001). All seven who presented syndrome interictal abnormalities on EEG. Conclusions: observed 11.2% (SLE) Antiphospholipid onset. Patients renal flares, onset, greater for follow-up. Recurrence 1.3% was syndrome.