Early Contrast-Enhanced Magnetic Resonance Imaging with Fluid-Attenuated Inversion Recovery in Multiple Sclerosis

摘要: OBJECTIVE Contrast-enhanced magnetic resonance imaging (MRI) with fluid-attenuated inversion recovery (contrast FLAIR) is particularly useful for the detection of meningeal lesions. However, whether contrast FLAIR in multiple sclerosis (MS) remains uncertain. This study evaluated usefulness MS. PATIENTS AND METHODS We prospectively studied clinical histories and brain MRI studies 6 patients clinically definite MS diagnosed according to new McDonald criteria. Contrast (repetition time [TR] 9,000 ms; echo [TE] 120 [TI] 2,200 5-mm slice thickness, a 1-mm interslice gap) was obtained use bolus gadolinium diethylenetriamine pentaacetic acid. RESULTS Three enhancing plaques located periventricular or juxtacortical areas showed higher intensity on than other MR sequences. In contrast, 8 deep white matter infratentorial no increased signals FLAIR. CONCLUSION Our findings suggest that early contrast-enhanced may be helpful further plaques, those