Pathogenesis of Experimental Tuberculosis in Animal Models

作者: D. N. McMurray , F. M. Collins , A. M. Dannenberg , D. W. Smith

DOI: 10.1007/978-3-642-80166-2_7

关键词:

摘要: Pathogenesis, in the context of an infectious disease, can be defined as temporal interplay between microbe and its host which ultimately results clinical illness. An understanding pathogenesis requires knowledge precise aggressive and/or evasive strategies employed by elucidation beneficial detrimental responses develops upon infection. The kinetics host-microbe interaction are at least important isolated activities either protagonist, since effectiveness counterstrategies is likely to depend environment confrontation occurs. For this reason, a disease like tuberculosis will only revealed studies course infection suitable host.

参考文章(93)
Arthur M. Dannenberg, John R. Esterly, Olivia T. Meyer, Takeshi Kambara, The local nature of immunity in tuberculosis, illustrated histochemically in dermal BCG lesions. Journal of Immunology. ,vol. 100, pp. 931- 941 ,(1968)
I. M. Orme, K. M. Dobos, B. Rivoire, P. J. Brennan, J. P. Griffin, A. D. Roberts, E. S. Miller, Dauhlian Chi, S. K. Furney, T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection : evidence for different kinetics and recognition of a wide spectrum of protein antigens Journal of Immunology. ,vol. 148, pp. 189- 196 ,(1992)
C. O. Siebenmann, C. Barbara, Quantitative evaluation of the effectiveness of Connaught freeze-dried BCG vaccine in mice and in guinea-pigs. Bulletin of The World Health Organization. ,vol. 51, pp. 283- 289 ,(1974)
D N McMurray, C L Mintzer, R A Bartow, R L Parr, Dietary Protein Deficiency and Mycobacterium Bovis BCG Affect Interleukin-2 Activity in Experimental Pulmonary Tuberculosis Infection and Immunity. ,vol. 57, pp. 2606- 2611 ,(1989) , 10.1128/IAI.57.9.2606-2611.1989
David N. McMurray, Rebecca A. Bartow, Immunosuppression and Alteration of Resistance to Pulmonary Tuberculosis in Guinea Pigs by Protein Undernutrition Journal of Nutrition. ,vol. 122, pp. 738- 743 ,(1992) , 10.1093/JN/122.SUPPL_3.738
S W Phalen, D N McMurray, T-lymphocyte response in a guinea pig model of tuberculous pleuritis. Infection and Immunity. ,vol. 61, pp. 142- 145 ,(1993) , 10.1128/IAI.61.1.142-145.1993