High Incidence of Chesst Malignancy Detected by FDG PET in Patients Suspected of Recurrent Squamous Cell Carcinoma of the Upper Aerodigestive Tract.

摘要: Objective: To determine the incidence of chest neoplasms detected by FDG PET in patients with previously treated squamous cell head and neck cancer (HNC), being evaluated for possible recurrent disease. Methods: This is aretrospective review 41 (M = 29, F 12: average age 58 years) HNC who underwent as part routine evaluation locoregional and/or distant recurrence. Thirty-four had advanced stage III or IV HNC. All studies were reviewed dedicated nuclear medicine physicians, including abnormal uptake chest. The findings correlated serial radiographs CT. occurrence rate incidental malignancy was determined based on characteristic imaging findings, biopsy, clinical course. Results: Twelve lungs mediastinum. Ten 12 found to have that could represent either metastases a new lung primary. Five these 10 unsuspected prior PET. other 2/12 scans false positive. There one false-negative PET, subsequent CT demonstrating pulmonary metastases. Overall, there 27% malignancies Conclusion: Our study demonstrated 1 out 4 spread. Fifty percent result suggests should be routinely included high-risk patients.