作者: Donald L Price , A Everette James , Edward Sperber , Ernst-Peter Strecker , None
DOI: 10.1001/ARCHNEUR.1976.00500010017003
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摘要: Chronic communicating hydrocephalus was produced in adult dogs by injection of silastic into the subarachnoid space. Electron microscopy used to verify sequence pathologic changes ventricular wall. The findings were correlated with cisternographic images and measurements cerebrospinal fluid (CSF) pressure. Early hydrocephalus, CSF pressure increased cisternograms showed entry clearing; ependyma stretched accumulated subependymal regions. In animals chronic normal disclosed radioactivity persisting ventricles. At this time severely damaged, white matter enlargement extracellular space, degenerative present axons myelin sheaths.