Mobile phase effects in liquid-solid chromatography

摘要: Abstract A comprehensive and detailed physicochemical model is presented for sample retention in liquid-solid chromatography, using either classical adsorbents such as silica or alumina, polar-bonded-phase packings aminoalkyl, diol, etc. Application of the to a large mass data wide variation adsorbent, mobile phase solute shows good agreement between theory experiment. The based upon displacement localization phenomena primary contributions retention. Localization can be sub-classified into at least four distinct effects, these latter effects correlated with geometry adsorption sites various adsorbents. preliminary solute—solvent hydrogen bonding liquid—solid chromatographic systems compared limited experimental data. effect significant systems.