Hydrogen sulphide poisoning: blood sulphide concentration and changes in haem metabolism.

摘要: Hydrogen sulphide is still a potential hazard in several occupations12 and especially sulphate pulp mills (P J?ppinen, academic dissertation) oil refineries. Blood may be used as an indicator of excessive human hydrogen exposure. Fatal concentrations are known.34 have been determined before by ion selective electrodes combined with Con way microdiffusion cells but only high concentrations, 1-70-3-75 mg/1, fatal cases could detected this method.4 Recently, the method using has improved preconcentration trapped sodium hydroxide solution.5 This new application allows blood determinations at low concen trations it thus suitable also for non-fatal poisonings. Although decreased activities haem synthesising enzymes, delta-aminolaevulinic acid syn thase (ALA-S) synthase (Haem-S) reported to occur workers exposed methyl mercaptan,6 difficult assess severity poisoning cases. The aim present work was evaluate usefulness thesising enzymes respect.