Intradiencephalon injection of histamine inhibited the recovery of locomotor function of spinal cord injured zebrafish
作者： Shu-Bing Huang , Hou-De Zhao , Lin-Fang Wang , Meng-Fei Sun , Ying-Li Zhu
DOI: 10.1016/J.BBRC.2017.05.158
关键词:
摘要: Human spinal cord injury (SCI) usually causes irreversible disability beneath the injured site due to poor neural regeneration. On the contrary, zebrafish show significant regenerative ability after SCI, thus is usually worked as an animal model for studying neuroregeneration. Most of the previous SCI studies focused on the local site of SCI, the supraspinal-derived signals were rarely mentioned. Here we showed that intradiencephalon injection of histamine (HA) inhibited the locomotor recovery in adult zebrafish post-SCI …
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