Endoscopic ultrasound-guided fine-needle aspiration and trucut biopsy in the diagnosis of gastric stromal tumors: a randomized crossover study.

摘要: Background and aim The diagnosis of gastrointestinal stromal tumors (GISTs) has important prognostic therapeutic implications. specific GIST to be based on immunocytochemistry. This study aimed prospectively compare in a crossover manner the accuracy endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) EUS-guided trucut biopsy (EUS-TCB) gastric GISTs. We hypothesized that EUS-TCB is superior EUS-FNA this respect. Patients methods Forty patients with subepithelial suspected basis EUS being underwent both EUS-TCB. sequence which techniques were employed was randomly assigned avoid bias. Results sampled (mean number passes: 2.1 +/- 0.9 EUS-TNB 1.9 0.8 EUS-FNA; P = not significant, NS). Final diagnoses were: (n 27), carcinoma 2), leiomyoma 1), schwannoma no possible 9). Device failure occurred 6 A cytohistological mesenchymal tumor 29) 2) made 70 % cases by 60 ( Among samples adequate, immunohistochemistry could performed 74 91 0.025). When inadequate included, overall diagnostic 52 55 There complications. Conclusions GISTs because high rate technical trucut. However, when an adequate sample obtained EUS-TCB, immunohistochemical phenotyping almost always possible. can safely set patients.