Magnetic resonance-detectable, ultrasound-detectable and/or radiopaque microcapsules and uses thereof
作者： Dara Lee Kraitchman , Jeff Bulte , Aravind Arepally , Bradley Powers Barnett
DOI:
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摘要: The present invention provides a microcapsule for implantation into mammalian body, comprising: a) at least one cell and/or bioactive agent; and b) biocompatible semi-permeable membrane encapsulating the cell, wherein comprises: polycationic polymer region, alginate paramagnetic or superparamagnetic metal that does not participate in crosslinking of polymer. further methods making microcapsules this use delivering cells therapeutic agents to subject embolization.
lens.org 参考文章(14)
Tully J. Speaker, Kenneth J. Sultzbaugh, Microcapsules of predetermined peptide(s) specificity(ies), their preparation and uses ,(1996)
Henry T. Brush, Charles C. Church, Howard Bernstein, Julie Ann Straub, Polymer-lipid microencapsulated gases for use as imaging agents ,(1997)
Kent C. Cochrum, Susan A. Jemtrud, Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method for preparation thereof ,(1997)
Karl C. Enevold, Method of solution overcoating with gelling polymer ,(1996)
Chandrashekhar Prabhakar Pathak, Implantable medical devices with fluorinated polymer coatings, and methods of coating thereof ,(2004)
Andrew C. A. Wan, Hanry Yu, Ser-Mien Chia, Kam W. Leong, Multi-layer cell encapsulation for tissue engineering ,(2001)
Bryan Baxter, Timothy Eng, Joe Zechlinski, April Zehm, Craig Atwood, Sivan Vadakkadath Meethal, Miguel Gallego, Kristyn Masters, Microencapsulation of cells ,(1993)
Robert Francis Workosky, Mark H. Anderson, Shuen-Cheng Hwang, James K. Tseng, Removal of nitric oxide from gas streams ,(1999)
John Kucharczyk, Michael E. Moseley, Method and apparatus for use with MR imaging ,(1997)
Nilesh Ron, Neil Desai, Francesco Curcio, Andrew S. Sojomihardjo, Patrick Soon-Shiong, Roswitha Heintz, Cytoprotective biocompatible containment systems for biologically active materials and methods of making same ,(2000)