Analyzing renal glomeruli with the new stereology.

摘要: The highly specialized architecture of the renal glomerulus is altered in a variety disease states. Morphometric methods, including stereological have been widely used to analyze these changes both animal and human glomeruli. However, many methods available until recently were biased provided incomplete information. past few years witnessed development new generation unbiased methods. Another advantage strategies that they are less influenced by technical artifacts than traditional This chapter describes how can be quantify glomerular morphology. Parameters considered include number volume; cell size; length, surface area, capillaries. Methods for obtaining data average glomeruli as well individual described. Technical details included wherever possible.